Hydroxychloroquine

Some information regarding Hydroxychloroquine

Pre exposure Hydroxychloroquine use is associated with reduced COVID19 risk in healthcare workers – a Retrospective cohort

SOURCE: https://www.medrxiv.org/content/10.1101/2020.06.09.20116806v3

Note: This article is a preprint and has not been certified by peer review. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.

Abstract

ABSTRACT BACKGROUND OF STUDY

While several trials are ongoing for treatment of COVID-19, scientific research on chemoprophylaxis is still lacking even though it has potential to flatten the curve allowing us time to complete research on vaccines.

OBJECTIVES OF THE STUDY

To explore the potential of HCQ as a pre-exposure prophylaxis for COVID 19 in health care workers in a tertiary care hospital.

MATERIALS & METHODS

We have conducted a retrospective cohort study among 106 Health Care Workers (HCW) exposed to COVID-19 patients, at a tertiary care hospital in India where there was an abrupt cluster outbreak within on duty personnel. HCWs who had voluntarily taken hydroxychloroquine (HCQ) prior to exposure were considered one cohort while those who had not were considered to be the Control group. All participants with a verifiable high risk contact history were tested for COVID-19 by RT-PCR.

RESULTS

The two cohorts were comparable in terms of age, gender, co-morbidities and exposure. The primary outcome was incidence rates of RT-PCR positive COVID-19 infection amongst HCQ users and Controls.  ······ [Read more] “Pre exposure Hydroxychloroquine use is associated with reduced COVID19 risk in healthcare workers – a Retrospective cohort”

‘Criminal’ ban on hydroxychloroquine based on ‘faulty’ study

26 Sep 2020 (source: Sky News Australia)

Liberal MP Craig Kelly says the ban placed on COVID-19 treatment hydroxychloroquine by Australian bureaucrats violates the Hippocratic Oath taken by doctors and is based on a study since proven false.

Mr Kelly said health bureaucrats interfered in the doctor-patient relationship by prohibiting the use of hydroxychloroquine even if the doctor thought the treatment would save the patient’s life.

Health bureaucrats have “violated the very first principle of the hypocritic oath” which is to ‘do no harm’,” he said.

Mr Kelly told Sky News technically bureaucrats should only ban the use of hydroxychloroquine if the evidence shows beyond all reasonable doubt that firstly, hydroxychloroquine doesn’t work and secondly, that it is dangerous.

“Recent studies show that proposition is no longer sustainable … and they must lift their bans otherwise they are engaged in crimes against humanity and they should be taken to the criminal court in the Hague,” he said.

“They are withholding medical treatment from Australians that the evidence shows can save their lives.”

Mr Kelly also said the National COVID-19 Clinical Evidence Taskforce which made the authoritative decision banning hydroxychloroquine rely upon the results of a flawed study conducted at the Oxford University.  ······ [Read more] “‘Criminal’ ban on hydroxychloroquine based on ‘faulty’ study”

An arduous consensus is taking root- the push for over the counter availability of HCQ in New Zealand

Author JJF (English), Tex Hill (Chinese)〈Himalaya New Zealand 〉

On the 19th of September, New Zealand’s largest local media, the New Zealand Herald published an Australian article regarding a double-blind experiment of hydroxychloroquine sulfate titled “Covid 19 coronavirus: Hydroxychloroquine: The drug that could be our saviour”.  For many local supporters of the whistle-blower movement, this was a pleasant surprise. Although the article was simply a reprint, the act of publishing the report itself is telling. We must acknowledge the promotional efforts made by all our supporters.

The reporting by local media regarding the truth of Covid-19 including HCQ has been extremely limited. What little is reported has been overwhelmingly negative. The New Zealand government allocated funds in April of this year to conduct research on the effectiveness of hydroxychloroquine and several other drugs in the treatment of the CCP virus. However, this effort was terminated within weeks supposedly due to a lack of positive case numbers in New Zealand. It is clear that the narrative effectively mirrors that of the World Health Organization (WHO).  Since then, HCQ has rarely been mentioned in New Zealand’s mainstream media. Even conducting a generic search for  ‘hydroxychloroquine’ as a keyword on government agency websites including the Ministry of Health and Parliament yield zero results.  ······ [Read more] “An arduous consensus is taking root- the push for over the counter availability of HCQ in New Zealand”

HCQ could be our savior

After more than two months of hard work, Himalaya NZ finally won the first positive response from mainstream media, calling for hydroxychloroquine sulfate to be an important means to control the epidemic.

HCQ could be our saviour, via

19 Sep, 2020 12:47pm/ NZ Herald

A divisive drug touted by Donald Trump may hold the secrets to stopping the spread of Covid-19, and its potential is huge.

Each morning before Claire Lobb sets off to work on the frontline of Victoria’s coronavirus second wave crisis, she pops a mysterious pill.

There’s a 50-50 chance that what she takes is hydroxychloroquine, a controversial drug touted by Donald Trump, that could stop millions of people around the world getting Covid-19

https://www.nzherald.co.nz/world/news/article.cfm?c_id=2&objectid=12366285

HCQ: the game-changer for New Zealanders

Author: Sugarpup
Editor: gravitationalwave (引力波)

Hydroxychloroquine (HCQ) has been the centre of a protracted political debate since March 2020, when President Trump cited the drug as a promising possible treatment for COVID19.

What is HCQ?

Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. It is believed that hydroxychloroquine interferes with the communication of cells in the immune system.

FDA approved HCQ 65 years ago, WHO calls it an essential medicine. It is also an approved medicine by Medsafe NZ.

Hydroxychloroquine Sulfate Tablets (200mg/tablet)

The big debate on the effectiveness of HCQ in treating COVID19

One of the drug’s famous critics is Dr Anthony Fauci – the director of the National Institute of Allergy and Infectious Diseases (NIAID), who is also one of the lead members of the White House Coronavirus Task Force. Dr Fauci insists that only randomised controlled trial evidence has any value in evaluating the effectiveness of HCQ in treating COVID19.  ······ [Read more] “HCQ: the game-changer for New Zealanders”

Will the coronavirus become weaker and gradually disappear?

Dr. Yan talks about whether the coronavirus may become weaker and gradually disappear, and how to overcome this virus


Jack:

Dr Yan we have a question from one of our audience members, it’s question number 9 for the avn crew and the question is: since covid 19 is still roaming around the country and not acting like a seasonal flu, does that mean it might be getting weaker and burning itself out? And I think she’s probably referencing perhaps the history of SARS-1 and i wondered if you could talk about that sort of potential decay of the virus?


Dr Yan:

Okay, so first i want to tell our audience that, yes, they have this idea because their idea based on this virus is some virus that comes from nature after the natural evolution, and finally this virus pathogen meets the host here. It means humans because humans are shown to be the best hosts in the world for SARS-CoV-2, but this thing’s based on the law of nature. And here we are talking about something special. We didn’t see this virus on the other natural kind of character like we see before. And according to what I said before, we analyse the genome and we see the evidence this virus actually is definitely not come from nature and it’s already been modified through the lab, those kinds of techniques.   ······ [Read more] “Will the coronavirus become weaker and gradually disappear?”

The Past and Present of HCQ

Written by Gravitational Wave

It is probably the first time in modern history that a kind of medicine is stigmatized as a victim of politic game. Yes, you know what I am going to talk about, hydroxychloroquine (HCQ). It is a long story. Please read it patiently, I believe you will come to your own judgment.

Antimalarials have been used as slow-acting drugs to treat rheumatism for more than a century. It originated from the bark of Cinchona tree in Peru. In 1820, two French pharmacists successfully extracted quinine, the earliest antimalarial drug in history, from the bark of cinchona. In 1894, a physician in London, England, used quinine to treat discoid lupus erythematosus (DLE) for the first time and achieved remarkable results. This was the first time that scientists used antimalarials to treat immune diseases.

Chloroquine is a chemically synthesized antimalarial drug based on quinine. With the development of science, scientists have discovered that chloroquine has obvious toxic and side effects while exerting therapeutic effects.So, in 1944, scientists developed a new type of antimalarial drug, hydroxychloroquine (HCQ), based on chloroquine. The difference between it and chloroquine is that a hydroxyl group is added to chloroquine, which has similar therapeutic effects but significantly reduces side effects.

Since then, hydroxychloroquine has been widely used as an immunosuppressant in the treatment of rheumatic diseases.  ······ [Read more] “The Past and Present of HCQ”